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Epilepsy Research
Volume 31, Issue 3
, Pages 175-186
, August 1998
Limbic epileptogenesis alters the anticonvulsant efficacy of phenytoin in Sprague–Dawley rats
References
- . Effects of phenobarbital and SC-13504 on partially kindled seizures in rats. Exp. Neurol. 1978;61:270–280
- . The anticonvulsant effects of diazepam and phenobarbital in prekindled and kindled seizures in rats. Neuropharmacology. 1981;20:597–603
- . Effects of carbamazepine, clonazepam, and phenytoin on seizure threshold in amygdala and cortex. Exp. Neurol. 1983;79:11–17
-
Bolwig, T.G., Trimble, M.R., 1989. The Clinical Relevance of Kindling. John Wiley & Sons, Chichester.
-
Cain, D.P., 1986. The transfer phenomenon in kindling. In: Wada, J.A. (Ed.), Kindling 3. Raven Press, New York, pp. 231–248.
- . Pharmacological modification of amygdaloid-kindled seizures. Neuropharmacology. 1980;19:1131–1136
-
DeLorenzo, R.J., 1995. Phenytoin. Mechanisms of action. In: Levy, R.H., Mattson, R.H., Meldrum, B.S. (Eds.), Antiepileptic Drugs, 4th ed. Raven Press, New York, pp. 271–282.
-
.
Phenytoin's effect on the spread of seizure activity in the amygdala kindling model.
Naunyn-Schmiedeberg's Arch. Pharmacol. 1997;356:341–347
- . The effect of interstimulation interval on the assessment and stability of kindled seizure threshold. Brain Res. Bull. 1981;7:629–633
- . Anticonvulsant effect of primidone in the gerbil. Time course and significance of the active metabolites. Pharmacology. 1984;28:329–335
- . Strategies for the development of drugs for pharmacoresistant epilepsies. Epilepsia. 1994;35(Suppl. 5):S10–S21
- . Kindling increases the sensitivity of rats to adverse effects of certain antiepileptic drugs. Epilepsia. 1995;36:763–771
-
Hvidberg, E.F., 1985. Monitoring antiepileptic drug levels. In: Frey, H.-H., Janz, D. (Eds.), Antiepileptic Drugs. Springer, Berlin, pp. 725–764.
-
Johannessen, S.I., Gram, L., Sillanpää, M., Tomson, T., 1995. Intractable Epilepsy. Wrightson Biomedical Publishing Ltd., Petersfield.
-
Jones, G.L., Wimbish, G.H., 1985. Hydantoins. In: Frey, H.-H., Janz, D. (Eds.), Antiepileptic Drugs. Springer, Berlin, pp. 351–420.
-
Jurna, I., 1985. Electrophysiological effects of antiepileptic drugs. In: Frey, H.-H., Janz, D. (Eds.), Antiepileptic Drugs. Springer, Berlin, pp. 611–658.
- . Seizures induced or aggravated by anticonvulsants. Epilepsia. 1986;27:706–710
- . Diphenylhydantoin activated seizures. Neurology. 1965;15:716–722
- . Basic aspects of epilepsy. Curr. Opin. Neurol. Neurosurg. 1993;6:223–232
- . Animal models of intractable epilepsy. Prog. Neurobiol. 1997;53:239–258
- . New visions in the pharmacology of anticonvulsion. Eur. J. Pharmacol. 1998;342:1–13
- . Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Res. 1988;2:145–181
-
.
High doses of memantine (1-amino-3,5-dimethyladamantane) induce seizures in kindled but not in non-kindled rats.
Naunyn-Schmiedeberg's Arch. Pharmacol. 1990;341:476–481
- . Responses to NMDA receptor antagonists altered by epileptogenesis. Trends Pharmacol. Sci. 1991;12:52
- . Kindling as a model of drug-resistant partial epilepsy: selection of phenytoin-resistant and nonresistant rats. J. Pharmacol. Exp. Ther. 1991;258:483–489
- . Strategies in antiepileptic drug development: is rational drug design superior to random screening and structural variation?. Epilepsy Res. 1994;17:95–134
- . Is amygdala kindling in rats a model for drug-resistant partial epilepsy?. Exp. Neurol. 1986;93:211–226
- . The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. III. Pentylenetetrazol seizure models. Epilepsy Res. 1991;8:171–189
- . Pharmacological characterization of phenytoin-resistant amygdala-kindled rats, a new model of drug-resistant partial epilepsy. Epilepsy Res. 1993;15:207–219
- . Pursuit of the mechanisms of kindling. Trends Neurosci. 1988;11:33–36
- . Cellular and molecular basis of epilepsy. J. Neurosci. 1994;14:3413–3425
- . Intravenous phenytoin is an effective anticonvulsant in the kindling model. Ann. Neurol. 1989;26:675–678
- . Phenytoin-induced seizures: a paradoxical effect at toxic concentrations in epileptic patients. Epilepsia. 1989;30:230–234
-
Paxinos, G., Watson, C., 1986. The Rat Brain in Stereotaxic Coordinates. Academic Press, Sydney.
- . Modification of seizure activity by electrical stimulation: II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 1972;32:281–294
- . Effects of procaine hydrochloride, diazepam, and diphenylhydantoin on seizure development in cortical and subcortical structures in rats. Electroencephalogr. Clin. Neurophysiol. 1975;38:355–365
- . Antiepileptic drugs: pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds. Pharmacol. Rev. 1990;42:223–286
- . Phenytoin potently increases the threshold for focal seizures in amygdala-kindled rats. Neuropharmacology. 1990;29:845–851
- . Kindling: basic mechanisms and clinical validity. Electroencephalogr. Clin. Neurophysiol. 1990;76:459–472
-
Schmidt, D., Morselli, P., 1986. Intractable Epilepsy: Experimental and Clinical Aspects. Raven Press, New York, NY.
- . The influence of seizure type on the efficacy of plasma concentrations of phenytoin, phenobarbital, and carbamazepine. Arch. Neurol. 1986;43:263–265
- . Behavioural analysis of amygdaloid kindling in Beagle dogs and the effects of clonazepam, diazepam, phenobarbital, diphenylhydantoin, and flunarizine on seizure manifestations. Exp. Neurol. 1979;64:579–586
- . Effects of acute and chronic phenytoin on the electrolyte content and the activities of Na+, K+, Ca2+, Mg2+, and HCO3−-ATPases and carbonic anhydrase of neonatal and adult cerebral cortex. Epilepsia. 1985;26:43–57
PII: S0920-1211(98)00029-1
© 1998 Elsevier Science B.V. All rights reserved.
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Epilepsy Research
Volume 31, Issue 3
, Pages 175-186
, August 1998
