Epilepsy Research
Volume 30, Issue 2 , Pages 115-126 , April 1998

Induction of convulsive seizures by acoustic priming in a new genetically defined model of epilepsy (Noda epileptic rat: NER)

  • Koji Iida

      Affiliations

    • Department of Neurosurgery, Hiroshima University School of Medicine, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734, Japan
  • ,
  • Masashi Sasa

      Affiliations

    • Department of Pharmacology, Hiroshima University School of Medicine, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81 82 2575140; fax: +81 82 2575144.
  • ,
  • Tadao Serikawa

      Affiliations

    • Institute of Laboratory Animals, Faculty of Medicine, Kyoto University, Sakyo-ku, Kyoto, 606-01, Japan
  • ,
  • Atsushi Noda

      Affiliations

    • Research Institute for Animal Science in Biochemistry and Toxicology, 3-7-11 Hashimotodai, Sagamihara, Kanagawa, 229, Japan
  • ,
  • Kumatoshi Ishihara

      Affiliations

    • Department of Pharmacology, Hiroshima University School of Medicine, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734, Japan
  • ,
  • Tomohide Akimitsu

      Affiliations

    • Department of Neurosurgery, Hiroshima University School of Medicine, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734, Japan
  • ,
  • Ryosuke Hanaya

      Affiliations

    • Department of Neurosurgery, Hiroshima University School of Medicine, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734, Japan
  • ,
  • Kazunori Arita

      Affiliations

    • Department of Neurosurgery, Hiroshima University School of Medicine, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734, Japan
  • ,
  • Kaoru Kurisu

      Affiliations

    • Department of Neurosurgery, Hiroshima University School of Medicine, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734, Japan

Received 23 June 1997 ,Revised 21 November 1997 ,Accepted 2 December 1997.

References 

  1. Browning RA, Nelson DK, Mogharreban N, Jobe PC, Laird II HE. Effect of midbrain and pontine tegmental lesions on audiogenic seizures in genetically epilepsy-prone rats. Epilepsia. 1985;26:175–183
  2. Browning RA, Wang C, Lanker ML, Jobe PC. Electroshock- and pentylenetetrazol-induced seizures in geneticaly epilepsy-prone rats (GEPRs): differences in threshold and pattern. Epilepsy Res. 1990;6:1–11
  3. Chauvel, P., Louvel, J., Kurcewicz, I., Debono, M., 1980. Epileptic seizures of the quaking mouse: electronical correlations. In: Baumann, N. (Ed.), Neurological Mutations Affecting Myelination. Elsevier, New York, pp. 513–516.
  4. Coenen AML, Drinkenburg WHIM, Inoue M, Van Luijtelaar ELJM. Genetic models of absence epilepsy, with emphasis on the WAG/Ril strain of rats. Epilepsy Res. 1992;12:75–86
  5. Collins, R.L., 1972. Audiogenic seizures. In: Purpura, D.P., Penry, J.K., Tower, B.D., Woodbury, D.M., Walter, R.D. (Eds.), Experimental Models of Epilepsy. Raven, New York, pp. 347–372.
  6. Faingold CL, Millan MH, Boersma CA, Meldrum BS. Excitant amino acids and audiogenic seizures in the genetically epilepsy-prone rat. I. Afferent seizure initiation pathway. Exp. Neurol. 1988;99:678–686
  7. Fuller JL, Collins RL. Temporal parameters of sensitization for audiogenic seizures in SJL/J mice. Dev. Psychobiol. 1968;1:185–188
  8. Fuller, J.L., Collins, R.L., 1970. Genetic and temporal characteristics of audiogenic seizures in mice. In: Welch, B.L., Welch, A.S. (Eds.), Physiological Effects of Noise. Plenum, New York, pp. 203–210.
  9. Hare JE, Hare AS. Epileptiform mice, a new neurological mutant. J. Hered. 1979;70:417–420
  10. Henry KR. Audiogenic seizure susceptibility induced in C57BL/6J mice by prior auditory exposure. Science. 1967;158:938–940
  11. Henry, K.R., Bowman, R.E., 1970. Acoustic priming of audiogenic seizures in mice. In: Welch, B.L., Welch, A.S. (Eds.), Physiological Effects of Noise. Plenum, New York, pp. 185–201.
  12. Jobe, P.C., 1981. Pharmacology of audiogenic seizures. In: Brown, R.D., Daigneault, E.A. (Eds.), The Pharmacology of Hearing. Experimental and Clinical Bases. Wiley Interscience, New York, pp. 271–304.
  13. Jobe, P.C., Mishra, P.K., Dailey, J.W., 1992. Genetically epilepsy-prone rats: Actions of antiepileptic drugs and monoaminergic neurotransmitters. In: Faingold, C.L., Fromm, G.H. (Eds.), Drugs for the Control of Epilepsy. CRC Press, Boca Raton, FL, pp. 253–275.
  14. Kiesmann M, Marescaux C, Vernes M, Micheletti G, Depaulis A, Warter JM. Audiogenic seizures in Wistar rats before and after repeated auditory stimuli: clinical, pharmacological, and electroencephalographic studies. J. Neural. Transm. 1988;72:235–244
  15. Marescaux C, Vernes M. Genetic absence epilepsy in rats from Strasbourg (GAERS). Ital. J. Neurol. Sci. 1995;16:113–118
  16. Maxson SC, Fine MD, Ginsburg BE, Koniecki DL. A mutant for spontaneous seizures in C57BL/10Bg mice. Epilepsia. 1983;24:15–24
  17. McCown TJ, Greenwood RS, Frye GD, Breese GR. Electrically elicited seizures from the inferior colliculus: A potential site for the genesis of Epilepsy?. Exp. Neurol. 1984;86:527–542
  18. Naritoku DK, Mecozzi LB, Aiello MT, Faingold CL. Repetition of audiogenic seizures in genetically epilepsy-prone rats induces cortical epileptiform activity and additional seizure behaviors. Exp. Neurol. 1992;115:317–324
  19. Noda, A., Hashizume, R., Tomizawa, Y., Ito, Y., Inoue, M., Asano, Y., Sasa, M., Serikawa, T., 1997. NER (Noda epileptic rats), A new type of genetic model in epilepsy research. Epilepsia (in press).
  20. Paxinos, G., Watson, C., 1982. The Rat Brain in Stereotaxic Coordinates. Academic Press, Sydney.
  21. Pierson MG, Swann J. Ontogenic features of audiogenic seizure susceptibility induced in immature rats by noise. Epilepsia. 1991;32:1–9
  22. Pierson M, Liebmann SL. Noise exposure-induced audiogenic seizure susceptibility in Sprague–Dawley rats. Epilepsy Res. 1992;13:35–42
  23. Reigel CE, Dailey JW, Jobe PC. The genetically epilepsy-prone rat: An overview of seizure prone characteristics and responsiveness to anticonvulsant drugs. Life Sci. 1986;39:763–774
  24. Sasa M, Hanaya R, Iida K, Akimitsu T, Kurisu K, Noda A, et al. A novel epilepsy animal model (NER). Jpn. J. Psychopharmacol. 1997;17:35–38
  25. Sasa M, Ohno Y, Ujihara H, Fujita Y, Yoshimura M, Takaori S, et al. Effects of antiepileptic drugs on absence-like and tonic seizures in the spontaneously epileptic rat, a double mutant rat. Epilepsia. 1988;29:505–513
  26. Saunders JC. Symposium: New data for noise standards. IV. The physiological effects of priming for audiogenic seizures in mice. Laryngoscope. 1974;4:750–756
  27. Seyfried TN, Yu RK, Glaser GH. Genetic analysis of audiogenic seizure susceptibility in C57BL/6J DBA/2J recombinant inbred strains of mice. Genetics. 1980;94:701–718
  28. Seyfried TN, Glaser GH. A review of mouse mutants as genetic models of epilepsy. Epilepsia. 1985;26:143–150
  29. Serikawa T, Yamada J, Ujihara H, Ohno Y, Sasa M, Takaori S. Ontogeny of absence-like and tonic seizures in the spontaneously epileptic rat. Lab. Anim. 1991;25:216–221
  30. Suzuki J, Nakamoto Y. Seizure patterns and electroencephalograms of El mouse. Electroenceph. Clin. Neurophysiol. 1977;43:299–311

PII: S0920-1211(97)00101-0

Epilepsy Research
Volume 30, Issue 2 , Pages 115-126 , April 1998