Evidence for increased cellular uptake of glutamate and aspartate in the rat hippocampus during kainic acid seizures: A microdialysis study using the `indicator diffusion' method

References 

1. Ben Ari, Y., Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy, Neuroscience, 14 (1985) 375–403.
2. Ben Ari, Y. and Represa, A., Brief seizure episodes induce long-term potentiation and mossy fibre sprouting in the hippocampus, Trends Neurosci., 13 (1990) 312–318.
3. Bloc, A., Samuel, D., Forni, C., Dusticier, N. and Kerkerian Le Goff, L., Effects of ionotropic excitatory amino acid receptor antagonists on glutamate transport and transport-mediated changes in extracellular excitatory amino acids in the rat striatum, J. Neurochem., 64 (1995) 1598–1604.
4. Bruhn, T., Christensen, T. and Diemer, N.H., Microdialysis as a tool for in vivo investigation of glutamate transport capacity in rat brain, J. Neurosci. Methods, 59 (1995) 169–174.
5. Bruhn, T., Cobo, M., Berg, M. and Diemer, N.H., Limbic seizure-induced changes in extracellular amino acid levels in the hippocampal formation: A microdialysis study of freely moving rats, Acta Neurol. Scand., 86 (1992) 455–461.
6. Casado, M., Bendahan, A., Zafra, F., Danbolt, N.C., Aragon, C., Gimenez, C. and Kanner, B.I., Phosphorylation and modulation of brain glutamate transporters by protein kinase C, J. Biol. Chem., 268 (1993) 27 313–27 317.
7. Crone, C., The permeability of capillaries in various organs as determined by use of the `indicator diffusion' method, Acta Physiol. Scand., 58 (1963) 292–305.
8. Danbolt, N.C., The high affinity uptake system for excitatory amino acids in the brain, Prog. Neurobiol., 44 (1994) 377–396.
9. Danbolt, N.C., Storm Mathisen, J. and Kanner, B.I., An [Na(+)+K(+)]coupled l-glutamate transporter purified from rat brain is located in glial cell processes, Neuroscience, 51 (1992) 295–310.
10. Glass, M. and Dragunow, M., Neurochemical and morphological changes associated with human epilepsy, Brain Res. Rev., 21 (1995) 29–41.
11. Johnston, G.A.R., Kennedy, S.M.E. and Twitchin, B., Action of the neurotoxin kainic acid on high affinity uptake of l-glutamic acid in rat brain slices, J. Neurochem, 32 (1979) 121–127.
12. Kanai, Y. and Hediger, M.A., Primary structure and functional characterization of a high-affinity glutamate transporter, Nature, 360 (1992) 467–471.
13. Kanai, Y., Smith, C.P. and Hediger, M.A., The elusive transporters with a high affinity for glutamate, Trends Neurosci., 16 (1993) 365–370.
14. Lallement, G., Carpentier, P., Collet, A., Pernot Marino, I., Baubichon, D. and Blanchet, G., Effects of soman-induced seizures on different extracellular amino acid levels and on glutamate uptake in rat hippocampus, Brain Res., 563 (1991) 234–240.
15. Leach, M.J., O'Donnell, R.A., Collins, K.J., Marden, C.M. and Miller, A.A., Effect of cortical kindling on [(3)H]d-aspartate uptake and glutamate metabolism in rats, Epilepsy Res., 1 (1987) 145–148.
16. Lehmann, A., Alterations in hippocampal extracellular amino acids and purine catabolites during limbic seizures induced by folate injections into the rabbit amygdala, Neuroscience, 22 (1987) 573–578.
17. Lehmann, A., Hagberg, H., Jacobson, I. and Hamberger, A., Effects of status epilepticus on extracellular amino acids in the hippocampus, Brain Res., 359 (1985) 147–151.
18. Lehre, K.P., Levy, L.M., Ottersen, O.P., Storm Mathisen, J. and Danbolt, N.C., Differential expression of two glial glutamate transporters in the rat brain: Quantitative and immunocytochemical observations, J. Neurosci., 15 (1995) 1835–1853.
19. Meldrum, B., Possible therapeutic applications of antagonists of excitatory amino acid neurotransmitters, Clin. Sci., 68 (1985) 113–122.
20. Millan, M.H., Chapman, A.G. and Meldrum, B.S., Extracellular amino acid levels in hippocampus during pilocarpine-induced seizures, Epilepsy Res., 14 (1993) 139–148.
21. Millan, M.H., Obrenovitch, T.P., Sarna, G.S., Lok, S.Y., Symon, L. and Meldrum, B.S., Changes in rat brain extracellular glutamate concentration during seizures induced by systemic picrotoxin or focal bicuculline injection: An in vivo dialysis study with on-line enzymatic detection, Epilepsy Res., 9 (1991) 86–91.
22. Nadler, J.V. and Cuthbertson, G.J., Kainic acid neurotoxicity toward hippocampal formation: Dependence on specific excitatory pathways, Brain Res., 195 (1980) 47–56.
23. Obrenovitch, T.P., Urenjak, J. and Zilkha, E., Evidence disputing the link between seizure activity and high extracellular glutamate, J. Neurochem., 66 (1996) 2446–2454.
24. Parsons, L.H. and Justice, J.B. Jr., Extracellular concentration and in vivo recovery of dopamine in the nucleus accumbens using microdialysis, J. Neurochem., 58 (1992) 212–218.
25. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, Sydney, 1982.
26. Pines, G., Danbolt, N.C., Bjoras, M., Zhang, Y., Bendahan, A., Eide, L., Koepsell, H.S., J, Seeberg, E. and Kanner, B.I., Cloning and expression of a rat brain l-glutamate transporter, Nature, 360 (1992) 464–466.
27. Prince Miller, H.K., Rothstein, J.D., Conn, P.J. and Levey, A.I., Modulation of glutamate transporter proteins in amygdala-kindled animals, Soc. Neurosci. Abstr., 21 (1995) 1859.
28. Rothstein, J.D., Dykes-Hoberg, M., Pardo, C.A., Bristol, L.A., Jin, L., Kunci, R.W., Kanai, Y., Hediger, M.A., Wang, Y., Schielke, J.P. and Welty, D.F., Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate, Neuron, 16 (1996) 675–686.
29. Schunzel, G., Wolf, G., Pomrenke, U., Pomrenke, C. and Schmidt, W., Pentylenetetrazol kindling and factors of glutamate transmitter metabolism in rat hippocampus, Neuroscience, 49 (1992) 365–371.
30. Sloviter, R.S., Possible functional consequences of synaptic reorganization in the dentate gyrus of kainate-treated rats, Neurosci. Lett., 137 (1992) 91–96.
31. Storck, T., Schulte, S., Hofmann, K. and Stoffel, W., Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain, Proc. Natl. Acad. Sci. USA, 89 (1992) 10955–10959.
32. Walker, M.C., Galley, P.T., Errington, M.L., Shorvon, S.D. and Jefferys, J.G.R., Ascorbate and glutamate release in the rat hippocampus after perforant path stimulation: A `dialysis electrode' study, J. Neurochem., 65 (1995) 725–731.