Epilepsy Research
Volume 91, Issue 1 , Pages 39-48 , September 2010

Inhibition of NMDA receptor/NO signaling blocked tolerance to the anticonvulsant effect of morphine on pentylenetetrazole-induced seizures in mice

  • Mehdi Ghasemi

      Affiliations

    • Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran
    • Present address: Institute for Cell Engineering, Departments of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
    • ,
  • Hamed Shafaroodi

      Affiliations

    • Pharmacology and Toxicology Department, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran
    • ,
  • Saeed Nazarbeiki

      Affiliations

    • School of Medicine, Shahed University of Medical Sciences, Tehran, Iran
    • ,
  • Hossein Meskar

      Affiliations

    • School of Medicine, Shahed University of Medical Sciences, Tehran, Iran
    • ,
  • Abbas Ghasemi

      Affiliations

    • Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran
    • School of Medicine, Iran University of Medical Sciences, Tehran, Iran
    • ,
  • Arash Bahremand

      Affiliations

    • Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran
    • ,
  • Pouya Ziai

      Affiliations

    • Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran
    • ,
  • Ahmad Reza Dehpour

      Affiliations

    • Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran
    • Corresponding Author InformationCorresponding author at: Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Poursina Ave., Keshavarz Boulvd., P.O. Box 13145-784, Tehran, Iran. Tel.: +98 21 6611 2802; fax: +98 21 6640 2569.

Received 5 December 2009 ,Revised 31 May 2010 ,Accepted 23 June 2010.

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PII: S0920-1211(10)00157-9

doi: 10.1016/j.eplepsyres.2010.06.010

Epilepsy Research
Volume 91, Issue 1 , Pages 39-48 , September 2010

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