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Epilepsy Research
Volume 88, Issue 2
, Pages 118-126
, February 2010
Region- and pattern-specific effects of glutamate uptake blockers on epileptiform activity in rat brain slices
References
- . Comparison of glutamine-enhanced glutamate release from slices and primary cultures of rat brain. Ann. NY Acad. Sci. 1995;765:72–85
- . Modification of epileptiform discharges in neocortical neurons following glutamate uptake inhibition. Epilepsia. 2005;46(Suppl. 5):129–133
- . Decreased glutamate transport enhances excitability in a rat model of cortical dysplasia. Neurobiol. Dis. 2008;32(2):254–261
- . EAAC1, a high-affinity glutamate transporter, is localized to astrocytes and gabaergic neurons besides pyramidal cells in the rat cerebral cortex. Cereb. Cortex. 1998;8:108–116
- . Homeostatic scaling of vesicular glutamate and GABA transporter expression in rat neocortical circuits. J. Neurosci. 2005;25:7121–7133
- . Strategies for metabolic exchange between glial cells and neurons. Respir. Physiol. 2001;129:71–81
- . Glutamate transporters prevent the generation of seizures in the developing rat neocortex. J. Neurosci. 2004;24:3289–3294
- . Episodic ataxia associated with EAAT1 mutation C186S affecting glutamate reuptake. Arch. Neurol. 2009;66:97–101
- . Hippocampal GABA transporter function in temporal lobe epilepsy. Nature. 1995;376:174–177
- . Plasticity of rat central inhibitory synapses through GABA metabolism. J. Physiol. 2001;535:473–482
- . Activity-dependent regulation of vesicular glutamate and GABA transporters: a means to scale quantal size. Neurochem. Int. 2006;48:643–649
- . Up-regulation of GAD65 and GAD67 in remaining hippocampal GABA neurons in a model of temporal lobe epilepsy. J. Comp. Neurol. 1999;412:488–505
- . Unaltered control of extracellular GABA-concentration through GAT-1 in the hippocampus of rats after pilocarpine-induced status epilepticus. Epilepsy Res. 2003;52:243–252
- . Refractory epilepsy: clinical overview. Epilepsia. 2007;48(Suppl. 1):3–7
- . A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: new insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2). Neuroscience. 2008;157:80–94
- . Kindling induces transient fast inhibition in the dentate gyrus—CA3 projection. Eur. J. Neurosci. 2001;13:1371–1379
- . Activity-dependent regulation of inhibitory synaptic transmission in hippocampal neurons. Nat. Neurosci. 2006;9:642–649
- . Fast homeostatic plasticity of inhibition via activity-dependent vesicular filling. PLoS ONE. 2008;3:e2979
- . Differential synaptic localization of the glutamate transporter EAAC1 and glutamate receptor subunit GluR2 in the rat hippocampus. J. Comp. Neurol. 2000;418:255–269
- . Synaptosomal glutamate and GABA transport in patients with temporal lobe epilepsy. J. Neurosi. Res. 2004;76:881–890
- . Association of l-glutamic acid decarboxylase to the 70-kDa heat shock protein as a potential anchoring mechanism to synaptic vesicles. J Biol. Chem. 2000;275:20822–20828
- . Glutamate transporters bring competition to the synapse. Curr. Opin. Neurobiol. 2004;14:346–352
- . Glutamate transporters and metabotropic receptors regulate excitatory neurotransmission in the medial entorhinal cortex of the rat. Brain Res. 2004;1027:151–160
- . Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures. Neurology. 2005;65:529–534
- . Demonstration of functional coupling between gamma-aminobutyric acid (GABA) synthesis and vesicular GABA transport into synaptic vesicles. Proc. Natl. Acad. Sci. U.S.A. 2003;100:4293–4298
- . Differentiation of substrate and nonsubstrate inhibitors of the high-affinity, sodium-dependent glutamate transporters. Mol. Pharmacol. 1999;56:1095–1104
- . Dynamic regulation of synaptic GABA release by the glutamate-glutamine cycle in hippocampal area CA1. J. Neurosci. 2006;26:8537–8548
- . Glutamate transporters: animal models to neurologic disease. Neurobiol. Dis. 2004;15:461–473
- . Neuronal glutamate uptake contributes to GABA synthesis and inhibitory synaptic strength. J. Neurosci. 2003;23:2040–2048
- . Inhibition of glutamate transporters results in a “suppression-burst” pattern and partial seizures in the newborn rat. Epilepsia. 2007;48:169–174
- . Effects of dihydrokainic acid on extracellular amino acids and neuronal excitability in the in vivo rat hippocampus. Neuropharmacology. 1987;26:1–8
- . GABA uptake and heterotransport are impaired in the dentate gyrus of epileptic rats and humans with temporal lobe sclerosis. J. Neurophysiol. 2001;85:1533–1542
- . Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron. 1996;16:675–686
- . Localization of neuronal and glial glutamate transporters. Neuron. 1994;23:713–725
- . GABA transporters and GABA-transaminase as drug targets. Curr. Drug Targets CNS Neurol. Disord. 2003;2:269–277
- . Presynaptic kainate receptor mediation of frequency facilitation at hippocampal mossy fiber synapses. Science. 2001;291:1972–1976
- . Penicillin-induced epileptiform activity in the hippocampal in vitro preparation. Ann. Neurol. 1977;1:463–469
- . A neuronal glutamate transporter contributes to neurotransmitter GABA synthesis and epilepsy. J. Neurosci. 2002;22:6372–6379
- . dl-Threo-beta-benzyloxyaspartate, a potent blocker of excitatory amino acid transporters. Mol. Pharmacol. 1998;53:195–201
- . Characterization of novel l-threo-beta-benzyloxyaspartate derivates, potent blockers of the glutamate transporters. Mol. Pharmacol. 2004;65:1008–1115
- . Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Science. 1997;276:1699–1702
- . Homeostatic plasticity in the developing nervous system. Nat. Rev. Neurosci. 2004;5:97–107
- . Role of glutamine and neuronal glutamate uptake in glutamate homeostasis and synthesis during vesicular release in cultured glutamatergic neurons. Neurochem. Int. 2005;47:92–102
- . Epileptiform activity in combined slices of the hippocampus, subiculum and entorhinal cortex during perfusion with low magnesium medium. Neurosci. Lett. 1986;69:156–161
PII: S0920-1211(09)00294-0
doi: 10.1016/j.eplepsyres.2009.10.006
© 2009 Elsevier B.V. All rights reserved.
« Previous
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Epilepsy Research
Volume 88, Issue 2
, Pages 118-126
, February 2010
