Epilepsy Research
Volume 87, Issue 1 , Pages 102-105 , November 2009

Abnormal parieto-motor connectivity in Tuberous Sclerosis Complex

  • Luigi D’Argenzio

      Affiliations

    • Paediatric Neurology and Psychiatry Unit, Neuroscience Department, Tor Vergata University, Rome, Italy
    • Corresponding Author InformationCorresponding author at: Paediatric Neurology and Psychiatry Unit, Neuroscience Department, Faculty of Medicine, Tor Vergata University of Rome, via Montpellier, 1, 00133 Rome, Italy. Tel.: +39 06 20900249.
    • ,
  • Giacomo Koch

      Affiliations

    • Neurology Clinic, Neuroscience Department, Tor Vergata University, Rome, Italy
    • IRCCS Fondazione Santa Lucia, Rome, Italy
    • ,
  • Roberta Bombardieri

      Affiliations

    • Paediatric Neurology and Psychiatry Unit, Neuroscience Department, Tor Vergata University, Rome, Italy
    • ,
  • Francesco Mori

      Affiliations

    • Neurology Clinic, Neuroscience Department, Tor Vergata University, Rome, Italy
    • IRCCS Fondazione Santa Lucia, Rome, Italy
    • ,
  • Romina Moavero

      Affiliations

    • Paediatric Neurology and Psychiatry Unit, Neuroscience Department, Tor Vergata University, Rome, Italy
    • ,
  • Diego Centonze

      Affiliations

    • Neurology Clinic, Neuroscience Department, Tor Vergata University, Rome, Italy
    • IRCCS Fondazione Santa Lucia, Rome, Italy
    • ,
  • Paolo Curatolo

      Affiliations

    • Paediatric Neurology and Psychiatry Unit, Neuroscience Department, Tor Vergata University, Rome, Italy

Received 24 March 2009 ,Revised 19 June 2009 ,Accepted 24 July 2009.

References 

  1. Curatolo P, Bombardieri R, Jozwiak S. Tuberous sclerosis. Lancet. 2008;372:657–668
  2. DiMario FJ. Brain abnormalities in tuberous sclerosis complex. J. Child Neurol. 2004;19:650–657
  3. Garaci FG, Floris R, Bozzao A, Manenti G, Simonetti A, Lupattelli T, et al. Increased brain apparent diffusion coefficient in tuberous sclerosis. Radiology. 2004;232:461–465
  4. Koch G, Fernandez Del Olmo M, Cheeran B, Ruge D, Schippling S, Caltagirone C, et al. Focal stimulation of the posterior parietal cortex increases the excitability of the ipsilateral motor cortex. J. Neurosci. 2007;27:6815–6822
  5. Koch G, Fernandez Del Olmo M, Cheeran B, Schippling S, Caltagirone C, Driver J, et al. Functional interplay between posterior parietal and ipsilateral motor cortex revealed by twin-coil transcranial magnetic stimulation during reach planning toward contralateral space. J. Neurosci. 2008;28:5944–5953
  6. Koch G, Oliveri M, Cheeran B, Ruge D, Lo Gerfo E, Salerno S, et al. Hyperexcitability of parietal-motor functional connections in the intact left-hemisphere of patients with neglect. Brain. 2008;131:3147–3155
  7. Koch G, Ribolsi M, Mori F, Sacchetti L, Codeca C, Rubino IA, et al. Connectivity between posterior parietal cortex and ipsilateral motor cortex is altered in schizophrenia. Biol. Psychiatry. 2008;64:815–819
  8. Leite JP, Neder L, Arisi GM, Carlotti CG, Assirati JA, Moreira JE. Plasticity, synaptic strength, and epilepsy: what can we learn from ultrastructural data?. Epilepsia. 2005;46(Suppl. 5):134–141
  9. Luat AF, Makki M, Chugani HT. Neuroimaging in tuberous sclerosis complex. Curr. Opin. Neurol. 2007;20:142–150
  10. Makki MI, Chugani DC, Janisse J, Chugani HT. Characteristics of abnormal diffusivity in normal-appearing white matter investigated with diffusion tensor MR imaging in tuberous sclerosis complex. AJNR Am. J. Neuroradiol. 2007;28:1662–1667
  11. Meador KJ. The basic science of memory as it applies to epilepsy. Epilepsia. 2007;48(Suppl. 9):23–25
  12. Roach ES, DiMario FJ, Kandt RS, Northrup H. Tuberous Sclerosis Consensus Conference: recommendations for diagnostic evaluation. National Tuberous Sclerosis Association. J. Child Neurol. 1999;14:401–407
  13. Rossini PM, Barker AT, Berardelli A, Caramia MD, Caruso G, Cracco RQ, et al Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application. Report of an IFCN committee. Electroencephalogr. Clin. Neurophysiol. 1994;91:79–92
  14. Rushworth MF, Taylor PC. TMS in the parietal cortex: updating representations for attention and action. Neuropsychologia. 2006;44:2700–2716
  15. Sosunov AA, Wu X, Weiner HL, Mikell CB, Goodman RR, Crino PD, et al. Tuberous sclerosis: a primary pathology of astrocytes?. Epilepsia. 2008;49(Suppl. 2):53–62
  16. Wong M. Mechanisms of epileptogenesis in tuberous sclerosis complex and related malformations of cortical development with abnormal glioneuronal proliferation. Epilepsia. 2008;49:8–21
  17. Ziemann U. TMS and drugs. Clin. Neurophysiol. 2004;115:1717–1729

PII: S0920-1211(09)00202-2

doi: 10.1016/j.eplepsyres.2009.07.009

Epilepsy Research
Volume 87, Issue 1 , Pages 102-105 , November 2009

Article Tools

* Image Usage & Resolution