« Previous
Next »
Epilepsy Research
Volume 87, Issue 1
, Pages 54-58
, November 2009
Is asymmetric dimethylarginine responsible for the vascular events in patients under antiepileptic drug treatment?
References
- . Heart disease mortality and morbidity in patients with epilepsy. Epilepsia. 1984;25(6):699–704
- . Antiepileptic drugs as independent predictors of plasma total homocysteine levels. Epilepsy Res. 2001;47(1–2):27–35
- . Folate, homocysteine and methionine loading in patients on carbamazepine. Acta Neurol. Scand. 2001;103(5):294–299
- . Tetatogenic effects of antiepileptic drugs: use of an International Database on Malformations and Drug Exposure (MADRE). Epilepsia. 2000;41:1436–1443
- . Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease. Circulation. 1997;95:2068–2074
- . Sudden unexpected death in epilepsy: a series from an epilepsy surgery program and speculation on the relationship to sudden cardiac death. J. Clin. Neurophysiol. 1991;8:216–222
- . Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia. Am. J. Physiol. Heart Circ. Physiol. 2008;295(2):816–825
- . Effects of long-term treatment with antiepileptic drugs on serum lipid levels in children with epilepsy. Neurology. 1995;45:1155–1157
- . Plasma homocysteine as a risk factor for vascular disease. JAMA. 1997;277:1775–1778
- . Hyperhomocysteinemia in children treated with antiepileptic drugs is normalized by folic acid supplementation. Epilepsia. 2005;46(10):1677–1683
- . Serum lipid levels during carbamazepine medication. Arch. Neurol. 1993;50:590–593
- . Homocyst(e)ine levels in patients on phenytoin therapy. Clin. Biochem. 1997;30(8):647–649
- . Homocysteine induces endothelial dysfunction via inhibition of arginine transport. J. Physiol. Pharmacol. 2007;58(June (2)):191–206
- . Asymmetric dimethylarginine plasma concentrations differ in patients with end-stage renal disease: relationship to treatment method and atherosclerotic disease. J. Am. Soc. Nephrol. 1999;10:594–600
- . Asymmetric dimethylarginine is associated with macrovascular disease and total homocysteine in patients with type 2 diabetes. Atherosclerosis. 2006;189(1):236–240
- . Hyperhomocysteinemia, endothelial dysfunction, and cardiovascular risk: the potential role of ADMA. Atheroscler. Suppl. 2003;4(4):61–65
- . Vascular determinants of epilepsy: the Rotterdam study. Epilepsia. 1997;38:1216–1220
- . Cognitive side effects of antiepileptic drugs in children. Neurology. 2004;62:872–877
- . Plasma high-density lipoprotein cholesterol inepileptics treated with anticonvulants. Eur. Neurol. 1980;19:67–72
- . Hematologic manifestations of longterm valproate therapy. Epilepsia. 1993;34:1098–1101
- . Endogenous nitric oxide synthase inhibitor: a novel marker of atherosclerosis. Circulation. 1999;99:1141–1146
- Cause-specific mortality in epilepsy: a cohort study of more than 9,000 patients once hospitalized for epilepsy. Epilepsia. 1997;38(10):1062–1068
- . Plasma total homocysteine concentrations in epileptic patients taking anticonvulsants. Metabolism. 1997;46(8):959–962
- . Elevated plasma concentrations of homocysteine in antiepileptic drug treatment. Epilepsia. 1999;40(3):345–350
- . Association between plasma homocysteine concentrations and extracranial carotid artery stenosis. N. Engl. J. Med. 1995;332:286–291
- . A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. JAMA. 1992;268(7):877–881
- . Asymmetric dimethyl-l-arginine (ADMA): a possible link between homocyst(e)ine and endothelial dysfunction. Curr. Drug Metab. 2005;6:3–14
- . Homocysteine, folate, vitamin B-12 and vitamin B-6 in patients receiving antiepileptic drug monotherapy. Epilepsy Res. 2000;40:7–15
- . Risk of acute coronary events and serum concentration of asymmetric dimethylarginine. Lancet. 2001;358:2127–2128
- . Importance of asymmetric dimethylarginine in cardiovascular risk. Lancet. 2001;358:2096–2097
- . Endogenous dimethylarginine as an inhibitor of nitric oxide synthesis. J. Cardiovasc. Pharmacol. 1992;20(Suppl. 12):60–62
- . Hyperhomocysteinaemia and endothelial dysfunction in young patients with peripheral arterial occlusive disease. Eur. J. Clin. Invest. 1995;25(March (3)):176–181
- . Hyperhomocysteinemia in children treated with sodium valproate and carbamazepine. Epilepsy Res. 2000;41(3):253–257
- . Elevated levels of plasma homocysteine and asymmetric dimethylarginine in elderly patients with stroke. Atherosclerosis. 2001;158:425–430
- . Determination of protein-incorporated methylated arginine reference values in healthy subjects whole blood and evaluation of factors affecting protein methylation. Clin. Biochem. 2008;41(14–15):1218–1223
☆ This study had presented as a poster at Eighteenth Meeting of the European Neurological Society 7–11 June 2008, Nice, France as entitled “Effects of valproic acid and carbamazepine monotherapies on asymmetric dimethylarginine, homocysteine, folate and vitamin B-12 levels: possible links to pathogenesis of epilepsy and complications of medication.”
PII: S0920-1211(09)00200-9
doi: 10.1016/j.eplepsyres.2009.07.011
© 2009 Elsevier B.V. All rights reserved.
« Previous
Next »
Epilepsy Research
Volume 87, Issue 1
, Pages 54-58
, November 2009
