Epilepsy Research
Volume 87, Issue 1 , Pages 88-94 , November 2009

Giant subcortical heterotopia involving the temporo-parieto-occipital region: A challenging cause of drug-resistant epilepsy

  • Federica Novegno

      Affiliations

    • Department of Pediatric Neurosurgery, Catholic University Medical School, Largo A. Gemelli, 8, 00168 Rome, Italy
    • Corresponding Author InformationCorresponding author. Tel.: +39 06 30154495.
    • ,
  • Domenica Battaglia

      Affiliations

    • Department of Child Neurology and Psychiatry, Catholic University Medical School, Rome, Italy
    • ,
  • Daniela Chieffo

      Affiliations

    • Department of Pediatric Neurosurgery, Catholic University Medical School, Largo A. Gemelli, 8, 00168 Rome, Italy
    • ,
  • Paolo Frassanito

      Affiliations

    • Department of Pediatric Neurosurgery, Catholic University Medical School, Largo A. Gemelli, 8, 00168 Rome, Italy
    • ,
  • Chiara Leoni

      Affiliations

    • Department of Child Neurology and Psychiatry, Catholic University Medical School, Rome, Italy
    • ,
  • Gianpiero Tamburrini

      Affiliations

    • Department of Pediatric Neurosurgery, Catholic University Medical School, Largo A. Gemelli, 8, 00168 Rome, Italy
    • ,
  • Luca Massimi

      Affiliations

    • Department of Pediatric Neurosurgery, Catholic University Medical School, Largo A. Gemelli, 8, 00168 Rome, Italy
    • ,
  • Tommaso Tartaglione

      Affiliations

    • Department of Radiology, Catholic University Medical School, Rome, Italy
    • ,
  • Concezio Di Rocco

      Affiliations

    • Department of Pediatric Neurosurgery, Catholic University Medical School, Largo A. Gemelli, 8, 00168 Rome, Italy
    • ,
  • Francesco Guzzetta

      Affiliations

    • Department of Child Neurology and Psychiatry, Catholic University Medical School, Rome, Italy

Received 23 May 2009 ,Revised 25 June 2009 ,Accepted 28 June 2009.

References 

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  8. Francione S, Kahane P, Tassi L, Hoffmann D, Durisotti C, Pasquier B, et al. Stereo-EEG of interictal and ictal electrical activity of a histologically proved heterotopic gray matter associated with partial epilepsy. Electroencephalogr. Clin. Neurophysiol. 1994;90(4):284–290
  9. Kuwahara M, Shima M, Nakai H, Nishino M, Fukuzumi A, Yoshioka A. A case of West syndrome with atypical massive gray matter heterotopia that is well controlled by ACTH therapy. Acta Paediatr. Jpn. 1996;38(3):274–277
  10. Meroni A, GAlli C, Bramerio M, Tassi L, Colombo N, Cossu M, et al. Nodular eterotopia: a neuropathological study of 24 patients undergoing surgery for drug-resistant epilepsy. Epilepsia. 2009;50(1):116–124
  11. Preul MC, Leblanc R, Cendes F, Dubeau F, Reutens D, Spreafico R, et al. Function and organization in dysgenic cortex. Case report. J. Neurosurg. 1997;87(1):113–121
  12. Tassi L, Colombo N, Cossu M, Mai R, Francione S, Lo Russo G, et al. Electroclinical, MRI and neuropathological study of 10 patients with nodular heterotopia, with surgical outcomes. Brain. 2005;128(Pt 2):321–337
  13. Villani F, Vitali P, Scaioli V, Rodriguez G, Rosa M, Granata T, et al. Subcortical nodular heterotopia: a functional MRI and somatosensory evoked potentials study. Neurol. Sci. 2004;25(4):225–229

PII: S0920-1211(09)00168-5

doi: 10.1016/j.eplepsyres.2009.06.006

Epilepsy Research
Volume 87, Issue 1 , Pages 88-94 , November 2009

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