Epilepsy Research
Volume 83, Issue 1 , Pages 66-72 , January 2009

Carisbamate, a novel neuromodulator, inhibits voltage-gated sodium channels and action potential firing of rat hippocampal neurons

  • Yi Liu

      Affiliations

    • Analgesics Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Welsh & McKean Roads, P.O. Box 776, Spring House, PA 19477-0776, United States
    • Corresponding Author InformationCorresponding author. Tel.: +1 215 628 5427; fax: +1 215 628 3297.
    • ,
  • George J. Yohrling

      Affiliations

    • CNS Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Welsh & McKean Roads, P.O. Box 776, Spring House, PA 19477-0776, United States
    • ,
  • Yan Wang

      Affiliations

    • Analgesics Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Welsh & McKean Roads, P.O. Box 776, Spring House, PA 19477-0776, United States
    • ,
  • Tasha L. Hutchinson

      Affiliations

    • Analgesics Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Welsh & McKean Roads, P.O. Box 776, Spring House, PA 19477-0776, United States
    • ,
  • Douglas E. Brenneman

      Affiliations

    • CNS Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Welsh & McKean Roads, P.O. Box 776, Spring House, PA 19477-0776, United States
    • ,
  • Christopher M. Flores

      Affiliations

    • Analgesics Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Welsh & McKean Roads, P.O. Box 776, Spring House, PA 19477-0776, United States
    • ,
  • Boyu Zhao

      Affiliations

    • CNS Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Welsh & McKean Roads, P.O. Box 776, Spring House, PA 19477-0776, United States

Received 28 April 2008 ,Revised 18 September 2008 ,Accepted 23 September 2008.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.

PII: S0920-1211(08)00277-5

doi: 10.1016/j.eplepsyres.2008.09.006

Epilepsy Research
Volume 83, Issue 1 , Pages 66-72 , January 2009

Article Tools

* Image Usage & Resolution