« Previous
Next »
Epilepsy Research
Volume 83, Issue 1
, Pages 44-51
, January 2009
No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy
References
- . Efficacy and tolerability of levetiracetam 3000
mg/d in patients with refractory partial seizures: a multicenter, double-blind, responder-selected study evaluating monotherapy. European Levetiracetam Study Group. Epilepsia. 2000;41:1276–1283 - . Defining intractability: comparisons among published definitions. Epilepsia. 2006;47:431–436
- . Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nat. Genet. 2003;33(Suppl.):228–237
- . Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case–control study. Lancet Neurol. 2007;6:970–980
- . Levetiracetam for partial seizures: results of a double-blind, randomized clinical trial. Neurology. 2000;55:236–242
- . Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A). PNAS. 1999;96:15268–15273
- . The long term retention of levetiracetam in a large cohort of patients with epilepsy. J. Neurol. Neurosurg. Psychiatry. 2006;77:101–103
- . Challenges and opportunities in the application of pharmacogenetics to antiepileptic drug therapy. Pharmacogenomics. 2006;7:89–103
- . Pharmacogenetics goes genomic. Nat. Rev. Genet. 2003;4:937–947
- . Predicting drug-resistant patients who respond to add-on therapy with levetiracetam. Seizure. 2006;15:387–392
- . Levetiracetam as add-on therapy in generalised epilepsies. Seizure. 2004;13:475–477
- . The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc. Natl. Acad. Sci. U.S.A. 2004;101:9861–9866
- . A Fortran Subroutine for Fisher Exact Test on Unordered Rxc Contingency-Tables. Acm Trans. Math. Software. 1986;12:154
- . Twenty-four-hour ambulatory blood pressure in men and women aged 17 to 80 years: the Allied Irish Bank Study. J. Hypertension. 1991;9:355–360
- . Genetic power calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics. 2003;19:149–150
- . Multicenter double-blind, randomized, placebo-controlled trial of levetiracetam as add-on therapy in patients with refractory partial seizures. European Levetiracetam Study Group. Epilepsia. 2000;41:1179–1186
- . A pilot study of compassionate use of Levetiracetam in patients with generalised epilepsy. J. Clin. Neurosci. 2004;11:728–731
- . Combining probability from independent tests: the weighted Z-method is superior to Fisher’s approach. J. Evol. Biol. 2005;18:1368–1373
PII: S0920-1211(08)00259-3
doi: 10.1016/j.eplepsyres.2008.09.003
© 2008 Elsevier B.V. All rights reserved.
« Previous
Next »
Epilepsy Research
Volume 83, Issue 1
, Pages 44-51
, January 2009
