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Epilepsy Research
Volume 24, Issue 3
, Pages 163-172
, July 1996
Dose-dependent metabolism of carbamazepine in humans
References
- . Carbamazepine plasma levels in children and adults: influence of age, dose, and associated therapy. Ther. Drug Monit. 1980;2:315–322
- . Early stage autoinduction of carbamazepine metabolism in humans. Eur. J. Clin. Pharmacol. 1994;47:355–360
- . Metabolism of carbamazepine and co-administered anticonvulsants during pregnancy. Epilepsy Res. 1995;21:65–75
- . Pharmacokinetics: time-dependent changes — autoinduction of carbamazepine epoxidation. J. Clin. Pharmacol. 1986;26:459–462
-
.
Relationship between carbamazepine concentration and extent of enzyme autoinduction.
Epilepsia. 1986;27:592
- . The pharmacokinetics of carbamazepine. Eur. J. Clin. Pharmacol. 1977;12:451–456
- . The bioavailability of carbamazepine. In: 4th Ed.. Proc. Aust. Assoc. Neurol. 12:1975;p. 123–128
-
.
Intermittent carbamazepine intoxication possibly related to altered absorption characteristics of the drug.
Med. J. Australia. 1987;146:313–316
- . Plasma kinetics of carbamazepine and its epoxide metabolite in man after single and multiple doses. Eur. J. Clin. Pharmacol. 1975;8:337–341
-
.
Carbamazepine. Chemistry and biotransformation.
In:
Levy RH, et al. editor. Antiepileptic Drugs. 4th Ed.. New York, NY: Raven; 1995;p. 499–513
-
.
Statistics with Confidence.
London, UK: British Medical Journal; 1988;
-
.
Pharmacokinetics of carbamazepine in normal humans after single and repeated oral doses.
J. Pharmacokin. Biopharm. 1976;4:521–535
- . Factors influencing plasma level/dose ratios of carbamazepine and its major metabolites in epileptic children. Ther. Drug Monit. 1990;12:438–444
- . Preliminary observations on the clinical pharmacology of carbamazepine (Tegretol). In: Proc. Aust. Assoc. Neurol. 11:1974;p. 189–198
-
.
Further observations on carbamazepine and carbamazepine-10,11-epoxide kinetics in epileptic patients.
In:
Gardner-Thorp C, et al. editor. Antiepileptic Drug Monitoring. Tunbridge Wells, UK: Pitman; 1977;p. 110–127
-
.
Autoinduction and steady-state pharmacokinetics of carbamazepine and its major metabolites.
Br. J. Clin. Pharmac. 1992;33:611–616
-
.
Pharmacokinetic implications of chronic drug treatment in epilepsy: carbamazepine.
In:
Benet LZ editors. The Effect of Disease States on Drug Pharmacokinetics. Washington, DC: American Pharmaceutical Association Academy of Pharmaceutical Sciences; 1976;p. 87–95
- . Pharmacokinetics of carbamazepine in normal man. Clin. Pharmacol. Ther. 1975;17:657–668
- . Factors influencing simultaneous concentrations of carbamazepine and its epoxide in plasma. Ther. Drug Monit. 1981;3:63–70
- . Effect of dose increments on serum carbamazepine concentration in epileptic patients. Clin. Pharmacokinet. 1980;5:576–582
- . Serum concentrations of carbamazepine and its epoxide and diol metabolites in epileptic patients: the influence of dose and comedication. Ther. Drug Monit. 1987;9:298–303
- . Relationship of intraindividual dose to plasma concentration of carbamazepine: indication of dose-dependent induction of metabolism. Ther. Drug Monit. 1989;11:533–539
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Epilepsy Research
Volume 24, Issue 3
, Pages 163-172
, July 1996
