Epilepsy Research
Volume 23, Issue 2 , Pages 149-155 , March 1996

A randomised open multicentre comparative trial of lamotrigine and carbamazepine as monotherapy in patients with newly diagnosed or recurrent epilepsy

  • Mauri Reunanen

      Affiliations

    • Department of Neurology, University of Oulu, Kajaanintie 50, FIN-90220 Oulu, Finland
    • ,
  • Mogens Dam

      Affiliations

    • University Clinic of Neurology, Hvidovre Hospital, DK-2650 Hvidovre, Denmark
    • ,
  • Alan W.C. Yuen

      Affiliations

    • Corresponding Author InformationCorresponding author.
    • The Wellcome Research Laboratories, Langley Court, Beckenham, Kent BR3 3BS, UK

Received 24 July 1995 ,Revised 31 August 1995 ,Accepted 25 September 1995.

References 

  1. Brodie MJ, Richens A, Yuen AWC. Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy. Lancet. 1995;345:476–479
  2. Chapman A, Yuen AWC, 106 Investigators . Lamotrigine (Lamictal) versus carbamazepine as monotherapy in patients with epilepsy. Epilepsia. 1994;35(suppl. 7):69
  3. Commission on Classification and Terminology of the International League Against Epilepsy . Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia. 1981;22:489–501
  4. Goa KL, Ross SR, Chrisp P. Lamotrigine. A review of its pharmacological properties and clinical efficacy in epilepsy. Drugs. 1993;46(1):152–176
  5. Matsuo F, et al.  Placebo-controlled study of the efficacy and safety of lamotrigine in patients with partial seizures. Neurology. 1993;43:2284–2291
  6. Richens A, Yuen AW. Overview of the clinical effects of lamotrigine. Epilepsia. 1991;32(suppl. 2):513–516
  7. Young DS. In: 2nd ed.. Effects of Drugs on Clinical Laboratory Tests. Vol. 3:Washington: AACC Press; 1990;p. 128–129
  8. Yuen AWC, Chapman A. Interim report on an open multicentre lamotrigine (Lamictal) vs carbamazepine monotherapy trial in patients with epilepsy. Can. J. Neurol. Sci. 1993;20(suppl. 4):S150

PII: 0920-1211(95)00085-2

Epilepsy Research
Volume 23, Issue 2 , Pages 149-155 , March 1996

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