Epilepsy Research
Volume 21, Issue 3 , Pages 171-182 , July 1995

Persistence of kindling: Effect of partial kindling, retention interval, kindling site, and stimulation parameters

  • Zoe Dennison

      Affiliations

    • Corresponding Author InformationTo whom reprint requests should be addressed. Present address: Department of Psychology, University College of the Fraser Valley, 33844 Marshall Rd., Abbotsford, British Columbia V2S 4N2, Canada.
    • Department of Psychology, University of Western Ontario, London, Ontario N6A 5C2, Canada
    • ,
  • G. Campbell Teskey

      Affiliations

    • Department of Psychology, University of Western Ontario, London, Ontario N6A 5C2, Canada
    • Present address: Department of Psychology, University of Calgary, Calgary, Alberta T2N 1N4, Canada.
    • ,
  • Donald P. Cain

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: (519) 679-2111 ext. 4628; Fax: (519) 661-396
    • Graduate Program in Neuroscience, University of Western Ontario, London, Ontario N6A 5C2, Canada

Received 14 September 1994 ,Accepted 10 March 1995.

References 

  1. Applegate CD, Burchfiel JL. Microinjections of GABA agonists into the amygdala complex attenuate kindled seizure expression in the rat. Exp. Neurol. 1988;102:185–189
  2. Burchfiel JL, Applegate CD. Stepwise progression of kindling: Perspectives from the kindling antagonism model. Neurosci. Biobehav. Rev. 1989;13:289–299
  3. Burchfiel JL, Applegate CD. Forebrain and brainstem mechanisms governing kindled seizure development: A hypothesis. In: 3rd edition.  Wada JA editors. Kindling. 4:New York: Plenum; 1990;p. 93–112
  4. Cain DP. Kindling and the amygdala. In:  Aggleton J editors. The Amygdala: Neurobiological Aspects of Emotion, Memory and Mental Dysfunction. New York: Wiley-Liss; 1991;p. 539–560
  5. Cain DP, Corcoran ME. Kindling with low-frequency stimulation: Generality, transfer and recruiting effects. Exp. Neurol. 1981;73:219–232
  6. Corcoran ME, McCaughran J, Wada JA. Acute antiepileptic effects of delta 9-tetrahydrocannabinol in rats with kindled seizures. Exp. Neurol. 1973;40:471–483
  7. Dennison Z, Teskey GC, Cain DP. Effect of a 12 week interval on permanence of ‘partial’ and ‘full’ kindling. Soc. Neurosci. Abstr. 1989;15:778
  8. Dennison Z, Tandan T, Teskey GC, Cain DP. The effect of a 12-week interval on permanence of ‘partial’ (stage 1), ‘full’ (stage 5) and low frequency (3 Hz) kindling in the rat. Soc. Neurosci. Abstr. 1990;16:1266
  9. Gilbert ME. The NMDA antagonist MK-801 suppresses behavioral seizures, augments afterdischarges, but does not block development of perforant path kindling. Epilepsy Res. 1994;17:145–156
  10. Goddard GV. The kindling effect: A precautionary note on therapeutic applications of localized brain stimulation. In:  Reynolds D,  Sjoberg A editor. Neuroelectric Research. Springfield, IL: Thomas; 1971;p. 37–39
  11. Goddard GV, McIntyre DC, Leech CK. A permanent change in brain function resulting from daily electrical stimulation. Exp. Neurol. 1969;25:295–330
  12. Homan RW, Goodman JH. Endurance of the kindling effect is independent of the degree of generalization. Brain Res. 1988;447:404–406
  13. Jimenez-Rivera C, Voltura A, Weiss GK. Effect of locus ceruleus stilulation on the development of kindled seizures. Exp. Neurol. 1987;95:13–20
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  16. Pinel JPJ, Phillips AG, Deol G. Effects of current intensity on kindled motor seizure activity in rats. Behav. Biol. 1974;11:59–68
  17. Racine RJ. The Modification of Afterdischarge and Convulsive Behavior in the Rat by Electrical Stimulation. Unpublished Ph.D. dissertation McGill University; 1969;
  18. Racine RJ. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroenceph. Clin. Neurophysiol. 1972;32:281–294
  19. Racine RJ. Modification of seizure activity by electrical stimulation: Cortical areas. Electroenceph. Clin. Neurophysiol. 1975;38:1–12
  20. Sato M, Racine RJ, McIntyre DC. Kindling: Basic mechanisms and clinical validity. Electroenceph. Clin. Neurophysiol. 1990;76:459–472
  21. Teskey GC, Ossenkopp K-P, Cain DP. Relationship of clectrographic measures to behavioral seizure development during amygdaloid kindling: A multivariate analysis. Soc. Neurosci. Abstr. 1988;14:833
  22. Wada JA. Amygdaloid and frontal cortical kindling in subhuman primates. In:  Girgis M,  Kiloh LG editor. Limbic Epilepsy and the Dyscontrol Syndrome. Amsterdam: Elsevier; 1980;p. 133–147
  23. Wada JA, Sato M, Corcoran ME. Persistent seizure susceptibility and recurrent spontaneous seizures in kindled cats. Epilepsia. 1974;15:465–478

PII: 0920-1211(95)00025-6

Epilepsy Research
Volume 21, Issue 3 , Pages 171-182 , July 1995

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